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Columbia University College of Physicians and Surgeons | Dementia: Update for the Practitioner
 
 Introduction
 
 Diagnosis of Mild Cognitive Impairment and Alzheimer's Disease
Karen L. Bell, M.D.
 
 Treatment Strategies for Dementia and Mild Cognitive Impairment
Mary Sano, Ph.D.
 
 Treatment of Depression, Agitation, and Psychosis in Dementia
Davangere P. Devanand, M.D.
 
 Recognition of Vascular Dementia, Dementia with Lewy Bodies, and Frontotemporal Dementia
Lawrence S. Honig, M.D., Ph.D.
 
  Neuropsychology of Mild Cognitive Impairment, Alzheimer's Disease, Dementia with Lewy Bodies, and Frontotemporal Dementia Penne Sims, Ph.D.
 
  What is Assessed
 
 
  Neuropsychology in Differential Diagnosis
 
 
  Screening Measures
 
 
  Protocol of a Declining Patient
 
 
 
  Protocol for Lewy Bodies
 
 
  Protocol for FTLD
 
 
  Benefits of Testing
 
  Neuroimaging in Dementia
Scott A. Small, M.D.
 
  Genetics of Neurodegenerative Disease: Alzheimer's Disease, Frontotemporal Dementia
Jennifer Williamson-Catania, M.S.
 
  Legal and Ethical Issues for Patients with Dementia
Daniel G. Fish, Esq.
 
 
Posttest
 
 
 
 
 
Accreditation
 
 
Reference List
 
 
Acknowledgements

 Begin page content 
Neuropsychology of Mild Cognitive Impairment,
Alzheimer's Disease, Dementia with Lewy Bodies,
and Frontotemporal Dementia
Penne Sims, Ph.D.

Protocol for Lewy Bodies
 
In cases of Lewy bodies, we typically see a memory disorder similar to that in AD. Unlike with AD, however, we see a greater visual-spatial deficit relative to other deficits in its profile, and we see some executive problems.
 
In the example of JC, a 71-year-old man with 12 years of education, there was no VIQ or PIQ testing here because JC was already a bit more progressed when he presented to us. JC's memory performance is very consistent with that of HW. On the SRT, the wordlist-learning task, he was able to recall three of five words, and he benefited from provision of cues presented in a recognition yes/no format.
 
     
Neuropsychological profile of LBD (JC)

-VIQ N/A
-PIQ N/A
-SRT-LTS 1%ile
-CLTR 5%ile
-Trial 6 5/12
-Delay 3/12
-Recog 9/12-
-VRI 3%ile
-VRII 8%ile
-CFL Fluency <1%ile
-Category Fluency 3%ile
-Naming 38/60 z=-3.18
-Rosen 3/5
-Orientation 3/10
-GDS 16/30
 
The neuropsychological profile of 71-year-old patient JC, diagnosed with Lewy-body disease.

Courtesy of Penne Sims, Ph.D.
 
 
We found JC to be moderately depressed, with a score of 16 out of 30 on the Geriatric Depression Scale (GDS). He also had some difficulties with construction, measured by the Rosen Drawing Test, named after the person who developed this particular task. This requires a person to perform a drawing task of various geometric figures of varying complexity.
 
The major point of note for JC is that we see poor scores on both, immediate and delayed visual memory. He was not able to encode visual information, in contrast to HW who, even when he had trouble with delay, was still able to encode the information.
 
 
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